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Pharmacol Rev 50:335356 Sipos K, Lange H, Fekete Z, Ullmann P, Lill R, Kispal G (2002) Maturation of cytosolic iron-sulfur proteins requires glutathione

Unfortunately, this is where NAC has gained a false reputation as a go-to drug if low glutathione (GSH) is suspected

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"Lowering homocysteine with B vitamins has no effect on biomarkers of bone turnover in older persons: a 2-y randomized controlled trial"

Prospective patients should consult physicians first to exclude systemic causes and thoroughly factor in costs and medical considerations before proceeding